Use this url to cite publication: https://hdl.handle.net/20.500.12512/98496
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Characteristics of invasive community-acquired staphylococcus aureus (CA-SA) infections in children: a European Multi-Centre study (PISA study) / M. Bellusci, I. Gimeno, B. Petraitiene, V. Zukovskaja, P. Sanchez, A. Noguera, D. Glikman, J. Saavedra, E. Cercenado, C. Montagnani, P. Kaiser-Labusch, L. Prieto, F. Chavez, B. Marcello, P. Rojo
Type of publication
Konferencijų tezės nerecenzuojamame leidinyje / Conference theses in non-peer-reviewed publication (T2)
Author(s)
Bellusci, M. | Department of Pediatrics, Hospital Universitario 12 de Octubre, Madrid, Spain |
Gimeno, I. | Department of Pediatrics, Hospital 12 de Octubre, Madrid, Spain |
Žukovskaja, Veslava | Vaikų ligoninė. Viešosios įstaigos Vilniaus universiteto ligoninės Santariškių klinikų filialas |
Sánchez, P. | Department of Pediatrics, Hospital Universitario Virgen del Rocío, Sevilla, Spain |
Noguera, A. | Department of Pediatrics, Hospital San Joan de Deu, Barcelona, Spain |
Glikman, D. | Department of Pediatrics, Western Galilee Hospital, Nahariya, Israel |
Saavedra, J. | Department of Pediatrics, Hospital Universitario Gregorio Marañon, Madrid, Spain |
Cercenado, E. | Department of Pediatrics, Hospital Universitario Gregorio Marañon, Madrid, Spain |
Montagnani, C. | Department of Pediatrics, Anna Meyer Childrens University Hospital, Florence, Italy |
Kaiser-Labusch, P. | Department of Pediatrics, Klinikum Bremen-Mitte Hospital, Bremen, Germany |
Prieto, L. | Department of Pediatrics, Hospital Universitario de Getafe, Getafe(Madrid), Spain |
Chavez, F. | Department of Microbiology, Hospital Universitario 12 de Octubre, Madrid, Spain |
Marcello, B. | Department of Pediatrics, Hospital Universitario 12 de Octubre, Madrid, Spain |
Rojo, P. | Department of Pediatrics, Hospital Universitario 12 de Octubre, Madrid, Spain |
Title
Characteristics of invasive community-acquired staphylococcus aureus (CA-SA) infections in children: a European Multi-Centre study (PISA study) / M. Bellusci, I. Gimeno, B. Petraitiene, V. Zukovskaja, P. Sanchez, A. Noguera, D. Glikman, J. Saavedra, E. Cercenado, C. Montagnani, P. Kaiser-Labusch, L. Prieto, F. Chavez, B. Marcello, P. Rojo
Publisher (trusted)
Kenes Group |
Date Issued
Date Issued |
---|
2014-05-06 |
Extent
p. 470-471, no. ESPID-0591.
Is part of
32nd annual meeting of the European Society for Paediatric Infectious Diseases - ESPID 2014 : May 6-10, 2014, Dublin, Ireland : abstracts / European Society for Paediatric Infectious Diseases. Geneva : Kenes Group, 2014.
Version
Originalus / Original
Field of Science
Abstract
Aims: The aim of the study was to describe the characteristics of invase CA-SA infections, the prevalence of CA-MRSA and to analyse factors related to the severity of invasive infection by CA-SA in children in Europe. Methods: A prospective, multi-centre European study was performed, analyzing epidemiological, clinical and microbiological data from 1-10-2012 to 30-09-2013. Severe infection was defined as an invasive infection that led to death or admission in the ICU because of hemodynamic instability, respiratory failure or other severe condition. Results: A total of 71 children (43 boys) were identified at ten European centres. Median age was 7.2 ± 5.4 years and 30% had a chronic disease. The most common primary diagnosis were bone or joint infections (58%; 14% being multifocal), pneumonia (21%) and bacteraemia (16%). The median hospital stay was 19.1±13.6 days. Fifteen patients (21%) needed ICU admission: mostly because of septic shock (median stay= 6.1 ± 6.8 days) and 6% died. At admission, median CRP, white cell-count and temperature value were 8.8 ± 8.7 mg/dl, 12600 ± 7200 cells/m3 and 38.8 ºC ± 0.8. Prevalence of methicillin and clindamycin resistance were 6% and 9%, respectively. When comparing non-severe cases with children with severe CA-SA infections, the latter had higher initial CRP values (16.1±10.8 vs 7.2±7.5, p<0.05) but no other differences were observed (sex, age, predisposing factors, site of infection, temperature, white cell count or antimicrobial resistance). Conclusions: Pediatric invasive CA-SA infections are severe in a significant number of cases. Methicillin resistance is still uncommon and does not seem to be related to severity. Higher CRP values at admission but not other variables are associated with the severity of infection.
Type of document
type::text::conference output::conference proceedings::conference paper
Other Identifier(s)
(LSMU ALMA)990000978570107106
Coverage Spatial
Airija / Ireland (IE)
Language
Anglų / English (en)