Use this url to cite publication: https://hdl.handle.net/20.500.12512/94741
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Influenza vaccine effectiveness during 2015-2016 influenza season: a hospital-based case-control study in Lithuania / Kuliese Monika, Jancoriene Ligita, Grimalauskaite Rita, Zablockiene Birute, Damuleviciene Gyte, Velyvyte Daiva, Lesauskaite Vita, Ambrozaitis Arvydas, Mickiene Aukse, Gefenaite Giedre
Type of publication
Tezės kitame recenzuojamame leidinyje / Theses in other peer-reviewed publication (T1e)
Author(s)
Jančorienė, Ligita | |
Zablockienė, Birutė | |
Ambrozaitis, Arvydas | |
Gefenaitė, Giedrė |
Title
Influenza vaccine effectiveness during 2015-2016 influenza season: a hospital-based case-control study in Lithuania / Kuliese Monika, Jancoriene Ligita, Grimalauskaite Rita, Zablockiene Birute, Damuleviciene Gyte, Velyvyte Daiva, Lesauskaite Vita, Ambrozaitis Arvydas, Mickiene Aukse, Gefenaite Giedre
Publisher (trusted)
Centre for Communicable Disease and AIDS (ULAC) |
Date Issued
Date Issued |
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2016-06-26 |
Extent
p. 41-41.
Is part of
Vilnius International Summit on Communicable Diseases : 26 June-1 July, 2016, Vilnius, Lithuania : abstract book / Centre for Communicable Disease and AIDS (ULAC) [et al.] ; Editor-in-chief: Saulius Caplinskas. Vilnius : Centre for Communicable Disease and AIDS (ULAC), 2016. ISBN 9789986720522.
Version
Originalus / Original
Series/Report no.
Poster.
Poster.
Description
ISBN 978-9986-720-52-2.
Field of Science
Abstract
Objectives. In Lithuania, one quarter of all acute respiratory tract annual infections are estimated to occur due to influenza. This virus might cause severe infection and lead to serious complications. The primary tool for preventing influenza is annual vaccination. Our primary objective was to measure seasonal influenza vaccine effectiveness (SIVE) against influenza in patients admitted to hospital during the 2015/2016 influenza season. We also described the co-circulation of other respiratory pathogens. Methods. A test-negative case-control study was conducted in three departments in the university hospitals in Lithuania. Data on demographic and clinical characteristics, including influenza vaccination status were collected from the patients recommended to receive SIV. Influenza and other respiratory pathogens were confirmed by multiplex RT-PCR. Results. One-hundred-sixty-three patients were included; 92(56.4%) subjects were 65 years old or older. Of the total sample, 15(9.2%) subjects were vaccinated against influenza at least two weeks before the onset of influenza symptoms, 12 vaccinated subjects were 65 years old or older. Sixty-five patients (39.9%) tested positive for influenza A (50 of which A(H1N1)pdm09; 15 unsubtyped), 8 (4.9%) for influenza B and 1 (0.6%) had a coinfection. The unadjusted SIVE against influenza in the total sample was 57% (95%CI: - 41% to 87%), and 43% (95%CI: -134% to 85%) in the group of subjects who were 65 years and older. Other respiratory pathogens found were coronavirus 3(1.9%), adenovirus 7(4.3%), rhinovirus 6(3.7%), metapneumovirus 7(4.3%), respiratory syncytial virus 8(4.9%), parainfluenza 1(0.6%). Two subjects within the sample were co-infected with influenza A and metapneumovirus, 2 with influenza A and adenovirus, 1 with influenza A and respiratory syncytial virus and 1 with influenza A and coronavirus. Conclusions. Due to low statistical power (partly due to that the study is still ongoing), the point estimate of m
Type of document
type::text::conference output::conference proceedings::conference paper
ISBN (of the container)
9789986720522
Other Identifier(s)
(LSMU ALMA)990000902590107106
Coverage Spatial
Lietuva / Lithuania (LT)
Language
Anglų / English (en)