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Assay of trace elements, thyroid gland and blood indices in children with alopecia / R. Naginiene, R. Kregzdyte, O. Abdrakhmanovas, S. Ryselis
Type of publication
Straipsnis Web of Science duomenų bazėje / Article in Web of Science database (S1a)
Title
Assay of trace elements, thyroid gland and blood indices in children with alopecia / R. Naginiene, R. Kregzdyte, O. Abdrakhmanovas, S. Ryselis
Publisher (trusted)
Dustri-Verlag Dr. Karl Feistle |
Is Referenced by
Elsevier BIOBASE/Current awareness |
Date Issued
Date Issued |
---|
2004-04-01 |
Extent
p. 207-210.
Is part of
Trace elements and electrolytes. Deisenhofen-Munich : Dustri-Verlag Dr. Karl Feistle, 2004, vol. 21, no. 4.
Version
Originalus / Original
Field of Science
Keywords
Abstract
Objective: Alopecia areata is considered an autoimmune hair loss disease, though its ethiopathophysiology remains not fully understood. Although medically benign, alopecia can cause tremendous emotional and psychological stress in affected patients and their families. There are claims that disbalance of trace elements, endocrine disorders or thyroid dysfunction may trigger the onset of alopecia. The aim of this trial was to assess the content of trace elements, hormones, blood indices and status of thyroid gland in children that have suffered from alopecia with various disseminations. Material and methods: The concentrations of lead, copper, manganese, chromium, cadmium, zinc and mercury in children (n = 80) from the Department of Pediatric Endocrinology, Hospital of Kaunas University of Medicine, hair, vein blood and spot urine were determined by AAS; the evaluation of blood indices, hormones and thyroid gland were performed as well. Results: The analysis extracted a significant increase in chromium and copper concentration in hair, and blood lead content whereas the amount of manganese in blood and zinc in urine of children with alopecia was lower compared to the reference group, respectively (p < 0.05). However, the findings showed no changes in the hormones and blood indices, though 57% of the children with alopecia had mild diffuse thyroid enlargement. Conclusions: No changes in blood, biochemical and hormonal indices in children with alopecia were established. The zinc deficiency induced by trace element replacements with heavy metals can cause the onset of alopecia in children or other sensitive population groups besides other factors. Furthermore, the content of heavy metals increase in organisms might produce accumulative effects, and hence may cause a deficiency of zinc which may trigger the onset of alopecia in children together with the appearance of thyreocele. Yet, more detailed analyses of these issues remain...
Type of document
type::text::journal::journal article
ISSN (of the container)
0174-7371
WOS
000224956800001
Other Identifier(s)
(LSMU ALMA)990000613780107106
Coverage Spatial
Vokietija / Germany (DE)
Language
Anglų / English (en)
Bibliographic Details
9
Journal | IF | AIF | AIF (min) | AIF (max) | Cat | AV | Year | Quartile |
---|---|---|---|---|---|---|---|---|
TRACE ELEMENTS AND ELECTROLYTES | 0.571 | 4.034 | 3.665 | 4.404 | 2 | 0.136 | 2004 | Q4 |
Journal | IF | AIF | AIF (min) | AIF (max) | Cat | AV | Year | Quartile |
---|---|---|---|---|---|---|---|---|
TRACE ELEMENTS AND ELECTROLYTES | 0.571 | 4.034 | 3.665 | 4.404 | 2 | 0.136 | 2004 | Q4 |