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Differences in retinal capillary blood flow and visual function in healthy male and female subjects of African and European descent / Brent A Siesky, Alon Harris, Nicholas Kalafatis, Louis R Pasquale, Aditya Belamkar, Joshua D. Shin, Ingrida Januleviciene, Giovanna Guidoboni, Alice Chandra Verticchio Vercellin
Type of publication
Tezės Web of Science duomenų bazėje / Theses in Web of Science database (T1a1)
Author(s)
Siesky, Brent A. | Icahn School of Medicine at Mount Sinai Hospital, New York, United States | |
Harris, Alon | Icahn School of Medicine at Mount Sinai Hospital, New York, United States | |
Kalafatis, Nicholas | Indiana University School of Medicine, Indianapolis, Indiana, United States | |
Pasquale, Louis R. | Icahn School of Medicine at Mount Sinai, New York, New York, United States | |
Belamkar, Aditya | Indiana University School of Medicine, Indianapolis, Indiana, United States | |
Shin, Joshua D. | New York Medical College, Valhalla, New York, United States | |
Guidoboni, Giovanna | University of Missouri, Columbia, Missouri, United States | |
Verticchio Vercellin, Alice Chandra | Icahn School of Medicine at Mount Sinai Hospital, New York, United States | Universita degli Studi di Pavia, Pavia, Lombardia, Italy |
Title
Differences in retinal capillary blood flow and visual function in healthy male and female subjects of African and European descent / Brent A Siesky, Alon Harris, Nicholas Kalafatis, Louis R Pasquale, Aditya Belamkar, Joshua D. Shin, Ingrida Januleviciene, Giovanna Guidoboni, Alice Chandra Verticchio Vercellin
Publisher (trusted)
Association For Research In Vision And Ophthalmology (Arvo) |
Is Referenced by
Date Issued
Date Issued |
---|
2021-06-21 |
Extent
p. 1-1.
Is part of
Investigative ophthalmology & visual science: IOVS : 2021 ARVO Annual Meeting abstract / Association for Research in Vision and Ophthalmology. Brookline Ma : Association For Research In Vision And Ophthalmology (Arvo), 2021, vol. 62, no. 8.
Version
Originalus / Original
Description
no. 548
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Field of Science
Abstract
Purpose : To investigate differences between retinal capillary blood flow and visual function in healthy male and female subjects of African (AD) and European (ED) descent. Methods : A total of 201 healthy subjects (171 ED, 30 AD) were evaluated for: systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), intraocular pressure (IOP) measured via Goldmann applanation tonometry, and calculations of ocular perfusion pressures: (OPP=2/3MAP-IOP), systolic OPP (SOPP=SBP-IOP), diastolic OPP (DOPP=DBP-IOP), and mean OPP (MOPP=MAP-IOP). Retinal blood velocities and the percentage of measured area without active retinal capillary blood flow (estimated as % of retina with no detectable flow) in the superior (SNF) and inferior (INF) superficial retina were assessed with Heidelberg Retinal Flowmetry. Visual function was assessed with both Early Treatment Diabetic Retinopathy Study (ETDRS) and Vector Vision contrast sensitivity (CS) charts. Unpaired t-tests were performed with p<0.05 considered statistically significant. Results : In all healthy subjects, the percentage non-vascularized retina was significantly higher in females compared to males in both the superior (SNF: 17.6%, vs. 15.5%; p=0.009) and inferior (INF: 18.1% vs. 14.6%; p=0.0002) superficial retina. There were no statistically significant differences in age between groups (female: 44.2 years, male: 43.3 years; p>0.05). The associated blood velocities were also significantly higher in females in both the superior and inferior retina (p=0.0003; p=0.0001, respectively). Healthy subjects of AD had significantly higher systemic blood pressures and all calculations of ocular perfusion pressures compared to those of ED (p<0.05). CS detection was significantly higher in males compared to females (CS Row D: 0.897 vs. 0.727; p=0.032) while [...].
Type of document
type::text::conference output::conference proceedings::conference paper
ISSN (of the container)
0146-0404
1552-5783
WOS
000690760500548
Other Identifier(s)
(LSMU ALMA)990001045950107106
Coverage Spatial
Jungtinės Amerikos Valstijos / United States of America (US)
Language
Anglų / English (en)
Funding(s)
Funding(s) | Project ID |
---|---|
United States Department of Health & Human Services | Ro1 EY015473 |
National Institutes of Health (NIH) - USA | R01EY030851 |
National Science Foundation (NSF) | 1853222/2021192 |
Journal | IF | AIF | AIF (min) | AIF (max) | Cat | AV | Year | Quartile |
---|---|---|---|---|---|---|---|---|
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE | 4.925 | 3.431 | 3.431 | 3.431 | 1 | 1.435 | 2021 | Q1 |
Journal | IF | AIF | AIF (min) | AIF (max) | Cat | AV | Year | Quartile |
---|---|---|---|---|---|---|---|---|
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE | 4.925 | 3.431 | 3.431 | 3.431 | 1 | 1.435 | 2021 | Q1 |
Journal | Cite Score | SNIP | SJR | Year | Quartile |
---|---|---|---|---|---|
Investigative Ophthalmology and Visual Science | 7.5 | 1.511 | 1.399 | 2021 | Q1 |