Use this url to cite publication: https://hdl.handle.net/20.500.12512/111861
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Seasonal Influenza Vaccine Effectiveness in Patients with Underlying Medical Conditions and Aged 65+ between 2015-2018 in Lithuania / Monika Kuliese, Ligita Jancoriene, Birute Zablockiene, Jurate Gudauskaite, Kotryna Krupeckaite, Rita Vilimaviciene, Daiva Velyvyte, Gyte Damuleviciene, Vita Lesauskaite, Arvydas Ambrozaitis, Alfredas Bagdonas, Aukse Mickiene, Giedre Gefenaite
Type of publication
Konferencijų tezės nerecenzuojamame leidinyje / Conference theses in non-peer-reviewed publication (T2)
Author(s)
Jančiorienė, Ligita | Viešoji įstaiga Vilniaus universiteto ligoninės Santaros klinikos | |
Zablockienė, Birutė | Viešoji įstaiga Vilniaus universiteto ligoninė Santaros klinikos | |
Ambrozaitis, Arvydas | Viešoji įstaiga Vilniaus universiteto ligoninė Santaros klinikos | |
Gefenaitė, Giedrė | Lund University, Sweden |
Title
Seasonal Influenza Vaccine Effectiveness in Patients with Underlying Medical Conditions and Aged 65+ between 2015-2018 in Lithuania / Monika Kuliese, Ligita Jancoriene, Birute Zablockiene, Jurate Gudauskaite, Kotryna Krupeckaite, Rita Vilimaviciene, Daiva Velyvyte, Gyte Damuleviciene, Vita Lesauskaite, Arvydas Ambrozaitis, Alfredas Bagdonas, Aukse Mickiene, Giedre Gefenaite
Date Issued
Date Issued |
---|
2019-08-28 |
Extent
p. 762-762.
Is part of
OPTIONS X for the Control of Influenza : abstracts : 28 August-1 September 2019, Suntec, Singapore / International Society for Influenza and other Respiratory Virus Diseases (ISIRV). Suntec : International Society for Influenza and other Respiratory Virus Diseases, 2019.
Version
Originalus / Original
Description
no. 10848
Topic: Public Health: Vaccine Effectiveness/Impact
Field of Science
Abstract
Introduction and Objectives: Due to lack of knowledge about seasonal influenza vaccine effectiveness (SIVE) against laboratory-confirmed influenza in patients with underlying conditions and aged 65+, a study to measure SIVE in hospitalised persons due to severe acute respiratory infection (SARI) in Lithuania during the 2015-2018 was conducted. The co-circulation of other respiratory viruses was also described. Methods: A test-negative case-control study was performed, with cases positive, and controls negative for laboratory-confirmed influenza. Crude SIVE and its 95% confidence intervals (95%CI) were calculated as (1-odds ratio)*100%. The analysis was not adjusted for sociodemographic and clinical characteristics, as they did not cahnge SIVE estimate by ≥10%. Influenza and other respiratory pathogens were detected with multiplex RT-PCR. Results: Overall 586 participants were recruited, 55(9.4%) of whom were vaccinated against influenza ≥2 weeks before the onset of SARI symptoms. Influenza was confirmed to 293(50%) subjects. Influenza A(H1N1)pdm09 was predominant in 2015-2016(69.4%), influenza A(H3N2) dominated in 2016-2017(93.2%), while influenza B/Yamagata was detected most often in 2017-2018(78.8%). SIVE in 2015-2016 influenza season was 57%(95%CI: -41%, 87%), and 70%(95%CI:-43%,94%) against any influenza and influenza A(H1N1)pdm09 respectively. SIVE in 2016-2017 influenza season was 42%(95%CI:-37%,76%) and 34%(95%CI:-58%,72%) against any influenza and influenza A(H3N2) respectively. SIVE in 2017-2018 influenza season was 62%(95%CI:-27%,88%), and 56%(95%CI:-43%,87%) against any influenza and influenza B/Yamagata respectively. All inall,respiratory pathogens found were similar in all the seasons: RSV 23(3,9%), rhinovirus 12(2,1%), metapneumovirus 13(2,2%), coronavirus 9(1,5%), adenovirus 9(0,3%). [...].
Type of document
type::text::conference output::conference proceedings::conference paper
Other Identifier(s)
(LSMU ALMA)990001044410107106
Coverage Spatial
Singapūras / Singapore (SG)
Language
Anglų / English (en)