Use this url to cite publication: https://hdl.handle.net/20.500.12512/110942
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Efficacy of Metronidazole Prior and after Surgery in Pain Control after Hemorrhoidectomy / Matas Pažusis, Žilvinas Saladžinskas, Tadas Latkauskas, Algimantas Tamelis
Type of publication
Konferencijų tezės nerecenzuojamame leidinyje / Conference theses in non-peer-reviewed publication (T2)
Title
Efficacy of Metronidazole Prior and after Surgery in Pain Control after Hemorrhoidectomy / Matas Pažusis, Žilvinas Saladžinskas, Tadas Latkauskas, Algimantas Tamelis
Publisher (trusted)
Baltic Association of Surgeons |
Date Issued
Date Issued |
---|
2021-06-03 |
Extent
p. 1-2.
Is part of
10th Congress of the Baltic Association of Surgeons (virtual event) : 3-5 June 2021, Rīga, Latvia / Latvian association of Surgeons. Rīga : Baltic Association of Surgeons, 2021.
Version
Originalus / Original
Description
Colorectal/ Proctology. Conference theme: Colorectal surgery / proctology. Presentation type: Oral Presentation
Field of Science
Abstract
Objectives: 1. To evaluate the efficacy of metronidazole prior and after surgery in relieving the severity of postoperative pain following Milligan-Morgan hemorrhoidectomy. 2. To evaluate the amount of analgesics used for postoperative pain relief. 3. To evaluate inflammatory blood markers during the administration of metronidazole. 4. To evaluate the clinical signs of the wound during the administration of metronidazole. 5. To evaluate the duration of pain sensation before the resumption of normal physical activity after hemorrhoidectomy when using metronidazole. Materials and Methods: A prospective matched pairs study was performed to compare the short-term treatment results between the study and the control groups. The study sample consisted of a total of 80 patients who underwent open hemorrhoidectomy for grade III or IV hemorrhoids at the Clinical Department of Surgery of the Hospital of the Lithuanian University of Health Sciences (LSMU) Kauno Klinikos during 2017-2019. Of these, 40 patients were administered metronidazole one day prior to and 7 days after the surgery (the study group), and 40 did not receive this drug (the control group). Results: During the investigated period 80 patients with median age of 50,5 years received excisional hemorrhoidectomy. Patients were divided into two groups: 40 study group and 40 control group. There were 15 men and 25 female in each group. There was no difference in operation time, number of hemorrhoids and grade. Postoperative pain at rest in the study and control group at day 1 was (0,97±1,31 vs 2,95±2,38 VAS), day 2 (0,78±1,36 vs 2,72±2,60 VAS), day 7 (0,42±1,23 vs 3,22±3,09 VAS) and day 14 (0,07±0,34 vs 2,50±2,64 VAS), a significant difference was found between groups, (p<0,05). Pain intensity during the first 14 days of defecation was significantly lower in the study group, (p<0,05). The total amount of ibuprofen consumed in the study group was 8.27 ± [...].
Type of document
type::text::conference output::conference proceedings::conference paper
Other Identifier(s)
(LSMU ALMA)990001037120107106
Coverage Spatial
Latvija / Latvia (LV)
Language
Anglų / English (en)