Laboratory of Ophthalmology
Address:Laboratory of OphthalmologyNeuroscience InstituteLithuanian University of Health SciencesEiveniu st. 4Kaunas LT-50009Lithuania Phone: +370 37 326749
Head of the laboratory
Rasa Liutkevičienė, PhD, firstname.lastname@example.org
Loresa Kriaučiūnienė, PhD, email@example.com
Alvita Vilkevičiūtė, firstname.lastname@example.org
Laboratory short history
Laboratory was established in 1992. The areas of scientific research are: epidemiologic investigation of eye diseases; complex ultrasonic investigation of structure, dimensions and haemodynamics of ocular tissue; storing and processing of ophthalmological images and signals for interactive and automatic multi-criterial clinical decision support. During collaboration with Sweden, Holland, Brazil in international E-Health and Telemedicine projects, infrastructure for scientific research in virtual environment was established. In 2003 Telemedicine centre of Kaunas University of Medicine (Lithuanian University of Health Sciences since 2011) was established, that is now institutional member of International Society for Telemedicine and e-Health (ISfTeH).
In the Laboratory 12 doctoral dissertations have been defended.
The Laboratory was awarded with eEurope Award for e-Health 2003 “e-Health NetLit (LT)" - a Finalist Diploma in a High Level Conference and Exhibition on e-Health, Brussels, 22, 23 April 2003.
Title: Relation of the eye neurosensoric function to genotype and fenotype in age related macular degeneration
Age related macular degeneration (AMD) – age related neurodegenerative disease of macula – central part of the retina. It leads to considerable visual loss. AMD is one of main causes of blindness in people in age over 60. Because of progressive loss of central visual function, it has marked influence to patient behaviour and life quality. In 2002 in Lithuania was 13.8% blind people because of AMD. In 2020 the amount of handicapped people because of AMD will increase to 16.5%. Unfortunately, today AMD is not treatable. However, up to now there is no proper treatment for age-related macular degeneration though novel treatment methods can stop progression of AMD and to help avoid blindness. That is why new information about pathogenesis of AMD can support development of the new methods of treatment and prevention of this disease.
Diagnosis, observation of course and treatment of AMD needs high resolution imaging technologies, parameterisation and high skilled ophthalmologist evaluation. Quantitative evaluation of this visual information could be achieved using biophysical models based imaging and quantitative evaluation methods.
Researchers of Laboratory of Ophthalmology in collaboration with Laboratory for Biophysics and Bioinformatics are planning to collaborate for biophysical models based biomedical signal and image analysis methods to process a big amount of information from biomedical signals, images, clearing up changes in eye neurosensoric function in AMD and reflecting the relation to genetic polymorpfisms. For this purpose some genetic markers (MMP-2 -1306C/T and -735C/T, MMP-3, -1171 5A/6A, MMP-9 -1562C/T, ApoE) will be investigated.
2015-2018 – project "Healthy and patients with age-related macular degeneration new genetic and metabolomic biomarkers search"
2015-2016 – collaboration in the Lithuanian-Japan project "Analysis of biomarkers, discovered by research using S.Pombe, in human blood"
2014-2016 – contribute in the project MIP-008/2014 " New molecular prognostic markers search in pituitary adenomas and associations with visual functions" funded by the Research Council of Lithuania
2013-2015 – post doc project BioMONDA "Multimodal data analysis of optic nerve and it's environment based on biophysical models", funded by the Research Council of Lithuania
|2011 - 2015 main publications (125 KB)|
Updated on 18th November 2016