Spausdinti

Laboratory of Molecular Neurobiology

Address:

Laboratory of Molecular Neurobiology
Neuroscience Institute
Lithuanian University of Health Sciences
Eiveniu st. 4
Kaunas LT-50009
Lithuania
 

Phone number:  +370 37 302967

 

Head of the Laboratory:

prof. Vilmantė Borutaitė, PhD,  vilmante.borutaite@lsmuni.lt

Personnel:

prof. Ilona Sadauskienė, PhD, ilona.sadauskiene@lsmuni.lt

Rasa Bernotienė, PhD, rasa.bernotiene@lsmuni.lt

Jurgita Šulinskienė, PhD, jurgita.sulinskiene@lsmuni.lt

Arūnas Liekis, PhD, arunas.liekis@lsmuni.lt

 

Laboratory history

In 1976, a group of scientists in Department of Biological and Bioorganic Chemistry began to study the biochemical peculiarities of energy generation in tissue repair. This group was the core of Pathochemistry Laboratory, founded in 1979. In 1982, the Laboratory was integrated into the structure of the Central Research Laboratory. Extending their scientific research, in 1983 some of the scientists assigned to the independent Laboratory of Physical and Chemical Research, renamed in 1988 into Laboratory of Clinical Chemistry. In 1992, the laboratories merged into the Laboratory of Pathochemistry of Institute for Biomedical Research. In 2011, the Laboratory of Pathochemistry was reorganized into the Laboratory of Molecular Neurobiology of Neuroscience Institute.

 

Research topic

Title: The role of the oxidative stress in aging

The aging appears to be one of the main reasons causing many of neurodegenerative diseases.This study is intended to evaluate the changes of the antioxidant defence system activity in the brain and other organs, during aging and to answer the question whether natural antioxidants are good for healthy aging. It is planned to assess the antioxidant defence system activity and lipid peroxidation of the laboratory animals of different ages; to determine the biochemical mechanisms of the impact of prooxidants in animal organs; to assess the effects of natural antioxidants on the cellular antioxidant defence system; and to evaluate the apoptosis in the organs of different ages animals, exposed to either prooxidants and antioxidants.

The results will be important both for researchers, working in the field of gerontology and for pharmaceutical specialists, developing natural medicines and supplements known to have antioxidant properties.

 

Main projects

The Laboratory participates in a project of the Advanced Pharmaceutical and Health Technologies Centre of Lithuanian University of Health Sciences. The researchers have access and are actively using open access facilities of the Laboratory for Pharmacological Regulation of Pathological Processes and Research of Drug Metabolism.

2011-2012 – joint LSMU and Institute of Public Health and Environment (Bilthoven, The Netherlands) project “Are supplements good for healthy ageing?”

 

International collaboration

Institute of Public Health and Environment (Bilthoven, The Netherlands), University of Aarhus (Denmark), University of New York (USA).

 

 pdf-logo.jpg (90x68, 68x68) 2011 - 2015 main publications (140 KB) 

 


Updated on 16th September 2016