Neuroscience Institute

  • About Institute

     

     

    Neuroscience Institute of Lithuanian University of Health Sciences was established in 2011 after reorganization of the Institute for Biomedical Research of Kaunas University of Medicine, which originated in 1957 when the Laboratory of Encephalography was established.

    Since 2018, the Behavioral Medicine Institute and Neuroscience Institute were merged, reserving the institution title  - Neuroscience Institute.

    Scientists working at the Institute are involved in basic, applied, and clinical research in various areas of neuroscience and behavioral medicine.

    Currently the Institute performs research programme "Research of nervous system for improvement of prognostic and therapeutic strategies".

    Since 2016, in collaboration with Departement of Neurosurgery of LUHS Hospital, is a partner of European reference network for rare adult cancers (solid tumours), subgroup Brain tumours (EURACAN).

    There are nine Departments (Research Laboratories) at the Neuroscience Institute, namely Laboratory of Biochemistry, Biophysics and Bioinformatics, Neurophysiology, Molecular Neurooncology,  Molecular Neurobiology, Toxicology, Ophthalmology, Behavioral Medicine, and Laboratory for Research of Pharmacological Regulation of Pathological Processes and Drug Metabolism. The Institute has a hospital Palangos Klinika where rehabilitation programmes for patients with cardiovascular diseases (after myocardial infarction, cardio surgery, coronary artery bypass graft surgery, after implantation of pacemaker, etc.) and treatment/rehabilitation of patients with stress related disorders (depression, anxiety, posttraumatic stress, chronic pain, fatigue and sleep disorders) are provided.

    The Institute has about 162 employees, among them there are 55 scientists and 19 research personnel (12 PhD students).

    Council of Neuroscience Institute, Lithuanian University of Health Sciences

     


    Updated on 16 April 2018

  • Main projects

     


    Updated on 28 May 2018

     

    2018-2020 – Lithuania–Japan collaboration program project “Investigation of molecular factors of Alzheimer’s disease: link between extracellular tau, beta-amyloid and neuroinflammation”, funded by the Research Council of Lithuania, head prof. R.Morkūnienė, participants prof. V. Borutaitė, K.Pampuščenko

    2018 – German Academic Exchange Service (DAAD) program project "Synaptic and dendritic dysfunction in Alzheimer‘s disease: computational and experimental neuroscience perspectives in understanding the dynamics of neurodegenerative processes", dr. A.Saudargienė

    2018 – LSMU-VDU funded project "Genetic predisposition to alcohol addiction and associated personality traits GVPRAVSAB", head dr. R.Jokubka

    2017-2021 – Global grant project No LMT-K-712-01-0131 "Dissecting ischemic brain injury: role of mitochondrial permeability transition pore in cells of developing and aging brain", head prof. V.Borutaitė

    2017-2021 – project No 01.2.2-LMT-K-718-01-0036 EXOTARGET „Exosome application for targeted drug delivery“, funded by the Research Council of Lithuania, head dr. A.Jekabsone

    2017-2021 – EU funded COST Action project CA16225 “Realising the therapeutic potential of novel cardioprotective therapies” (EU-CARDIOPROTECTION), prof. V.Borutaitė, dr. O.Arandarčikaitė

    2017-2021 – EU funded COST Action project CA16207 "Problematic Internet Use", managament committee members dr. A.Bunevičius, dr. J.Burkauskas

    2017-2021 – contribute in the EC programme Horizon 2020 funded project HBM4EU (The European Human Biomonitoring Initiative), Grant agreement No. 733032, dr. L.Strumylaitė

    2017-2020 – project No S-MIP-17-108 "The prognostic value of miRNA classifier as a novel tool for prediction of glioma patient outcome and response to therapy", funded by the Research Council of Lithuania, head dr. P. Vaitkienė

    2017-2020 – collaboration in the project No S-MIP-17-257 "Psychosocial suicide risk factors and accessibility of help in the environment of persons’ who committed suicide", funded by the Research Council of Lithuania, V.Liaugaudaitė

    2017-2019 – EC programme Horizon 2020 M-Era.Net project No S-M-ERA.NET-17-2 „Engineering and functionalization of delivery system with Pelargonium sidoides biologically active substance on inflamed periodontal surface area“ (PELARGODONT), co-coordinator dr. A.Jekabsone

    Main projects of Behavioral Medicine Institute, 2010-2016

    2016-2020 – EU funded COST Action project MITOEAGLE “Mitochondrial mapping: Evolution - Age - Gender - Lifestyle - Environment", Lithuania deputy prof. V.Borutaitė

    2016-2018 – contribute in the EC programme Horizon 2020 funded project ID 650003 “EU FET Flagship Human Brain Project”, dr. A.Saudargienė

    2016-2017 – collaboration in the LSMU-KTU project "Elaboration and employment of virtual reality stimuli to investigate peripheral vestibular function (VIRVEST)", dr. R.Liutkevičienė

    2016 – project No PR16-82 "Imaging of live tissue/models' mimetics", supported by Joint Stock Company Ferentis, dr. A.Jekabsone

    2015-2018 – collaboration in the project No SEN-01/2015 „Optimizing the effectiveness of Hyperthermic chemotherapy by modulation of heat shock proteins, energy resources and adhesion in malignant cells“, funded by the Research Council of Lithuania, dr. S.Trumbeckaitė

    2015-2018 – collaboration in the project No SEN-07/2015 „Novel systems of prodrug activation for the cancer gene therapies“, funded by the Research Council of Lithuania, dr. A.Kazlauskas

    2015-2018 – project No SEN-11/2015 "New genetic and metabolic biomarkers search in healthy subjects and patients with age-related macular degeneration", funded by the Research Council of Lithuania, head prof. V.P.Deltuva

    2015-2018 – project No MIP‐44/2015 BRAINflame "Psychological distress, inflammatory factors, brain natriuretic peptide and outcomes of patients with brain tumor", funded by the Research Council of Lithuania, head dr. A.Bunevičius

    2015-2018 – project No MIP-52/2015 GlioProSer "Quantitative serum profiles estimation of proteins related to glioma angiogenesis and invasiveness”, funded by the Research Council of Lithuania, head dr. D.Skiriutė

    2015-2016 – collaboration in the Lithuanian-Japan project "Analysis of biomarkers in human blood, discovered by research using S.pombe", head dr. R.Liutkevičienė

    2015-2016 – collaboration in EU Horizon 2020 project No 664339 HEALTH-TECH “Centre of Excellence in Science and Technology for Healthy Ageing", prof. V.Borutaitė

    2015 – project "In vitro investigation of interaction of cells with customer's prototypic hydrogel samples", managed by Lithuanian Business Promotion Agency, head dr. A.Jekabsone

    2014-2016 – contribute in the project MIP-008/2014 "New molecular prognostic markers search in pituitary adenomas and associations with visual functions", funded by the Research Council of Lithuania, dr. R.Liutkevičienė

    2014-2015 – collaboration in the Lithuanian-Ukrainian project "Identification and characterization of novel biomarkers for human glial tumors", head dr. P.Vaitkienė

    2014-2015 – collaboration in the LSMU-KTU project "Elaboration of innovative device to investigate peripheral vestibular function", dr. R.Liutkevičienė

    2013-2015 – EU funded COST Action project FA 1005 INFOGEST "Improving health properties of food by sharing our knowledge on the digestive process", members of Executive committee dr. J.Liobikas, dr. S.Trumbeckaitė

    2013-2015 – post doc project BioMONDA "Multimodal data analysis of optic nerve and it's environment based on biophysical models", funded by the Research Council of Lithuania, head prof. A.Kriščiukaitis, dr. Asta Kybartaitė-Žilienė

    2012-2016 – EC 7FP project No 318652 OpenScienceLink: Open Semantically-enabled, Social-aware Access to Scientific Data, Lithuania deputy dr. A Bunevičius

    2012-2015 – contribute in the Global grant project* VP1-3.1-ŠMM-07-K-02-060 „Gene-Environment Interactions Connecting Low Triiodothyronine Syndrome and Outcomes of Cardiovascular Disease (GET-VASC)”, dr. D.Skiriutė, dr. R.Naginienė

    2012-2015 – Global grant project* VP1-3.1-ŠMM-07-K-02-059 „Investigation of sensory information processing and attention mechanisms by employing genetic modification of neuronal act", head dr. T.Tkatch

    2012-2015 – contribute in the Global grant project* VP1-3.1-ŠMM-07-K-02-062 "Energetic, genetic and epigenetic mechanisms of resistance to chemotherapy induced apoptosis in pancreatic cancer", dr. S.Trumbeckaitė

    2012-2014 – project MIP-045/2012 „Nicotinic modulation of neuronal column activity", funded by the Research Council of Lithuania, head habil.dr. A Kuras

    2012-2014 – project LIG-12003 "Gene expression and function-based identification of biomarkers for diagnosis of glioma malignancies", funded by the Research Council of Lithuania, head dr. A.Kazlauskas

    2012-2014 – project LIG-04/2012 MALPAMA "Molecular mechanisms of pathogenesis of Alzheimer’s disease” (in collaboration with Institute of Biochemistry, and Institute of Biotechnology of Vilnius University, Department of Neurology of Lithuanian University of Health Sciences Hospital), funded by Research Council of Lithuania, head prof. R.Morkūnienė

    2012-2014 – ESF project VP1-3.1-ŠMM-08-K-01-022 „Implementation of R&D activities of Medicine National Research Programmes in clinical and molecular research of fundamental cardiology, neurosciences, and digestive systems“, dr. G.Svirskis, prof. V.Borutaitė

    2012-2014 – contribute in the project LIG-12002 STELLATA „Investigation of activity and redox status of Pancreatic Stellate Cells", funded by the Research Council of Lithuania, dr. S.Trumbeckaitė

    2011-2015 – Global grant project* VP1-3.1-ŠMM-07-K-01-130 “Mitochondria, nitric oxide and cytochrome c reducing agents in protection against brain and heart ischemia-reperfusion injury”, head prof. V.Borutaitė

    2011-2014 – project SVE-11008 HIBRIDAI „Interspecific hybrids of orchard plant – a novel source of anthocyanins“, funded by the Research Council of Lithuania, head dr. J.Liobikas

    2011-2012 – project MIP-11298 “Interactions between tectal neuronal responses evoked by two visual stimuli”, funded by the Research Council of Lithuania, head dr. G.Svirskis

    2011-2012 – joint LSMU and Institute of Public Health and Environment (Bilthoven, The Netherlands) project “Are supplements good for healthy ageing?”, head habil.dr. L.Ivanov

    2010-2011 – project “Low T3 syndrome impact on the outcomes after the brain tumour surgery”, funded by the Research Council of Lithuania, head dr. V.P.Deltuva

    2010-2011 – project „Investigation of synaptic co-transmission in frog retinotectal synapses“, funded by the Research Council of Lithuania, head habil.dr. A.Kuras

    2010-2011 – project „The investigation for new combinations of clinical and epigenetic markers in diagnosis and prognosis“, funded by the Research Council of Lithuania, head prof. A.Tamašauskas

     2010-2011 – collaboration in project „Multivariate analysis based non invasive evaluation of central haemodynamics and prognosis of patient status” No. MIP-68/2010, funded by Research Council of Lithuania, head prof. A.Kriščiukaitis

    2010-2011 – project MIP-10182 "The evaluation of biological activity and technological functionalization of lectins", dr. J.Liobikas, dr. D.Majienė

    2009 – project No T-64/09 "The assessment of the relationship between cadmium and the risk of breast cancer", funded by Lithuania State Science and Studies Foundation, head dr. L.Strumylaitė

    2008-2010 – project AMILOIDE “Detection of pathogenic beta-amyloid oligomers for diagnostics of Alzheimer’s disease”, funded by Lithuania State Science and Studies Foundation, head prof. V.Borutaitė

    2008 – project “Implication of bistability of frog recurrent tectal neurons in the activation of NMDA receptors”, funded by Lithuania State Science and Studies Foundation, head habil.dr. A.Kuras

    2007-2011 – EU funded COST Action project FA0602 MITOFOOD (A research community for nutritional optimization of mitochondrial function for health promotion and disease resistance), Lithuania deputy prof. V.Borutaitė

    2007-2009 – post doc project "Research on molecular markers of recurrence in benign and malignant meningiomas", funded by Lithuania State Science and Studies Foundation, head prof. A.Tamašauskas, dr. D.Skiriutė

    2007-2009 – EC 6FP project SSPE-CT-2007-044159 PRONET (Pollution Reduction Options Network), Lithuania deputy dr. R.Naginienė

    2007 – project “Investigation of dendritic currents elicited in frog tectum neurons by individual retinotectal input”, funded by Lithuania State Science and Studies Foundation, head habil.dr. A.Kuras

    2006-2011– EC 6FP project FOOD-CT-2006-016253 PHIME (Public Health Impact of Long-term, Low-level Mixed Element Exposure in Susceptible Population Strata), Lithuania deputy dr. R.Naginienė

    2006-2009 – EUREKA project E! 3694 PROPOCREAM „The development of the multifunctional semisolid preparations from natural products“, dr. D.Majienė

    2006-2008 – ESF project ESF/2004/2.5.0-03-385/BPD-210/ES2006-01 "Implementation of advanced studies for medical physics technologies and nanophotonics", dr. K.Skauminas

    2006-2008 – ESF project BPD2004-ERPF-1.5.0-12-05/0035 “Centre for science and studies of medical physics technologies and nanophotonics”, dr. K.Skauminas

    2006-2007 – EC 6FP Marie Skłodowska-Curie project MERG-CT-2006-044907 MITOCHONDRIA & ABETA (Mitochondria and beta-amyloid in brain ischemia/reperfusion), dr. A.Jekabsone

    2006 – project “Intraoperative fluorescentic imaging of brain tumour gliomas”, funded by Lithuania State Science and Studies Foundation

    2005-2008 – ESF project BPD2004-ESF-2.5.0-01-04/0046 "The development of master's, residency and PhD study programs in Pharmacy, Biochemistry, Biotechnology and Genetics for students of Medicine and Pharmacy", habil.dr. L.Ivanov

    2005-2007 – Implementation the EU Council Directive 77/312EEB on Biological Screening of the Population for Lead, dr. R.Naginienė

    2005 – project “Investigation of influence of frog moving-edge detector on tectal neuron network”, funded by Lithuania State Science and Studies Foundation, head habil.dr. A.Kuras

    2004-2007 – EC 5FP project 2004127 EMFnEAR (Exposure at UMTS electromagnetic fields: study on potential adverse effects on hearing), Lithuania deputy prof. I.Ulozienė

    2004-2006 – EC 6FP Marie Skłodowska-Curie project CT-2004-010313 MITOCHONDRIA (Role of nitric oxide/oxygen competition at mitochondria in neuronal death during ischemia and/or inflammation), dr. A.Jekabsone

    2004 – project „NMDA receptor activation in frog tectum neurons“, funded by Lithuania State Science and Studies Foundation, head habil.dr. A.Kuras

    2003-2005 – EC 5FP project QLK4-2002-02395 PINCHE (Policy Interpretation Network on Children’s Health and Environment), Lithuania deputy dr. R.Naginienė

     2001-2004 – EC 5FP project QLRT-2001-00150 GUARD (Potential adverse effect of GSM cellular phone on hearing), Lithuania deputy prof. I.Ulozienė

      

         *  Global Grant measure is being managed using ESF funding, by implementation of a project “Execution of functions assigned to Lithuanian Research Council for implementation of the measure No. VP1-3.1-ŠMM-07-K “Support for scientific research by scientists and other researchers (Global Grant)” project No. VP1-5.1-FM-01-V-02-001. Project is being funded by European Social Fund (ESF) under the Human Resources Development Action Programme.

     

     

     

     

  • Main publications

  • Main conferences

    Updated on 15 June 2018

    Main international scientific events

     

    Professor Taisuke Tomita (Laboratory of Neuropatholgy and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Japan) presented the lecture „Understanding the molecular/cellular pathology and emerging strategies against Alzheimer disease”. The lecture took place on 15 June 2018 at the Faculty of Pharmacy, audience A-205, Sukilėlių pr. 13, Kaunas.

     -

    Coorganise of The 6th BalticNordic School on Neuroinformatics BNNI2018: Understanding the Brain: from Neuroscience to Deep Learning. The school took place on 11-13 June 2018 at the Ventspils University of Applied Sciences, Latvia.

     -

    A group of scientists from Ben-Gurion University of the Negev (BGU, Israel) visited the Neuroscience Institute and on 4-5 June 2018 presented the lectures:

    • "Physiological role and mode of regulation of mitochondrial Ca2+ signaling and metabolism interrogated by imaging and optometabolic control" - prof. Israel Sekler, Faculty of Health Sciences, Department of Physiology and Cell Biology, BGU.
    • "Sodium fluxes and excitability of thin neuronal processes" - assoc. prof. Ilya Fleidervish, Faculty of Health Sciences, Department of Physiology and Cell Biology, BGU.
    • "Minimally invasive neurosurgery. The keyhole concept" - Israel Melamed, neurosurgeon, Department of Neurosurgery, Soroka Medical Centre, BGU.

    -

    The IX International Conference of Lithuanian Neuroscience Association Neurodiversity: from theory to clinics, organised by Neuroscience Institute, in collaboration with Lithuanian Neuroscience Association (LNA), Lithuanian University of Health Sciences and Vytautas Magnus University. The conference took place at the Lithuanian University of Health Sciences, Kaunas, Lithuania, on 1 December 2017. More information and program is available here.

    -

    Representatives from the ENIGMA Consortium (enigma.ini.usc.edu) were giving a seminar on 12th October 2017. The seminar was held at the Faculty of Pharmacy at the Lithuanian University of Health Sciences. The programme:

    • The ENIGMA Consortium: Mapping Human Brain Diseases with Imaging and Genomics in 50,000 Individuals from 35 Countries - prof. Paul Thompson.
    • Imaging Biomarkers of Recovery after Traumatic Brain Injury: The Need for Consortium Studies - prof. Emilly Dennis.

    -

    The 5th BalticNordic School on Neuroinformatics (BNNI2017): Theoretical modeling of brain functions in neurological and psychiatric disorders: Advancing future neuroscience and medicine through Neuroinformatics methods. The School took place on 6-7 October 2017 at the Neurosience Institute of Lithuanian University of Health Sciences. More information is available here.

    -

    The 1st BalticNordic Summer School on Neuroinformatics (BNNI2013): Computations in the Brain and Translational Neuroscience (together with Tampere Technical University (Finland) and Vytautas Magnus University (Lithuania). The Summer School took place on 29-31 May 2013, in Vytautas Magnus University, Kaunas, Lithuania. More information can be found at http://www.cs.tut.fi/sgn/neuroinfo/index_files/Page500.htm

    -

    International Translational Neuroscience Conference, which was held on 16-17 June 2011 in Kaunas, Lithuania. The conference was dedicated to the 60th Anniversary of Neurosurgery in Lithuania and establishment (onwards the 1st July 2011) of Neuroscience Institute of Lithuanian University of health Sciences. More information is available at http://www.neuroscience.lt

    -

    Co-organiser of the Mitochondrial Physiology Society summer school "MiP summer 2010", which was held on 10-16 June 2010 in Druskininkai, Lithuania. More information is available at http://www.mitophysiology.org/index.php?id=mipsummer2010

     


  • National and international awards

    _______________________________________________________________________________________________

    Updated 15 March 2018

     

    • Prof. Arimantas Tamašauskas, head of the Department of Neurosurgery and director of Neuroscience Institute,  -  The Order of the Lithuanian Grand Duke Gediminas "Knight's Cross" for the merits to the Republic of Lithuania and international glorification of the Republic; awarded by the President of the Republic of Lithuania Dalia Grybauskaitė on 6 July 2017.
    • Dr. Adomas Bunevičius, senior researcher at the Laboratory of Clinical Research, Neuroscience Institute,  - BrainLab Neurosurgery Award at the Congress of Neurological Surgeons in Boston, USA on 7-11 October 2017, for a neurosurgeon working outside the USA for the outstanding research on brain tumors. 
    • Prof. Vilmantė Borutaitė, head of the Laboratory of Biochemistry, Neuroscience Institute, - Osvalds Šmidebergs Medal of Latvian Society of Pharmacology, 2012.
    • Prof. Adolfas Toleikis, prof. Vilmantė Borutaitė and prof. Vida Mildažienė, Laboratory of Biochemistry, Neuroscience Institute, - Science Award of  Lithuania (2008) for the outstanding research “The mechanisms of response to stress and control of mitochondrial functions”.
    • Dr. Rima Naginienė, senior researcher at the Laboratory of Toxicology of Neuroscience Institute, - Award of the Romanian Society for Magnesium Research, 2007.
    • Dr. Rima Naginienė, researcher at the Laboratory of Toxicology, Neuroscience Institute, - Faustus Scientific Award, Austria, 2004.
    • Dr. Silvija Jankevičiūtė, junior researcher at the Laboratory of Biochemistry, Neuroscience Institute - "Art in Science" award for poster "Sky-blue snowdrop" exhibited in public areas in Lithuanian cities.
  • Contacts

    Address:

    Neuroscience Institute
    Lithuanian University of Health Sciences
    Eiveniu st. 4
    Kaunas LT-50161
    Lithuania

     

    Phone: +370 37 302951
    Fax: +370 37 302959
    E-mail: neuro@lsmuni.lt

     

     
    Director prof. Arimantas Tamašauskas, Habil.Sc.
    Phone: +370 37 302951, arimantas.tamasauskas@lsmuni.lt

     

    Depurty director for Research Rima Naginienė, PhD
    Phone: +370 37 302953, neuro@lsmuni.lt

     

    Referent Milda Ablingė
    Phone: +370 37 302951, referente.neuro@lsmuni.lt
     
     
     

    Address:

    Hospital Palangos Klinika at Neuroscience Institute
    Lithuanian University of Health Sciences
    Vyduno Str. 4/ J. Sliupio Str. 7
    Palanga LT-00135
    Lithuania

     

    Phone: +370 460 30012
    Fax: +370 460 30014
    E-mail: palangos.klinika@lsmuni.lt

     

    Reception:
    Phone: +370 460 30027
    Mobile: +370 618 41860
     
     
    Deputy director for Clinic Vesta Steiblienė, MD, PhD
    Phone: +370 460 30011; +370 460 30012, vesta.steibliene@lsmuni.lt

     

     
     
     

    For Laboratories and research personnel contacts please refer to the section "Laboratories"

     


    Updated on 19 June 2018