Spausdinti

Research projects of Laboratory of Clinical and Molecular Gastroenterology

Participation in projects:

  1. "Development of novel methods for gut mircobiome modification" (grant no. 09.3.3-LMT-K-712-01-0130), project leader: dr. J. Skiecevičienė, funding source: EU structural fund, duration: 2018-2021.
  2. "Multi-layer omics approach to gastric cancer: circulating biomarker profiling in the blood on genetic, epigenetic and microbiome levels (MULTIOMICS)" (grant no. 09.3.3-LMT-K-712-01-0130), project leader: dr. J. Skiecevičienė, funding source: EU structural fund, duration: 2018-2021.
  3. "IsomiR in the pathogenesis of colorectal cancer: from miRNome-wide bioinformatic analysis to their functional validation" (grant no.  S-MIP-17-22), project leader: prof. G. Kiudelis, funding source: Research Council of Lithuania, duration: 2017-2020.
  4. "Gastric microbiome: twin study" (grant no. APP-2/2016), project leader: dr. J. Skiecevičienė, funding source: Research Council of Lithuania, duration: 2016-2019.
  5. "The aging gut: genetic and enteric nervous system alterations in intestinal diverticulosis" (grant no. SEN-06/2015), project leader: prof. A. Tamelis, funding souce: Research Council of Lithuania, duration: 2015-2018.
  6. “MicroRNA Profiling in Tissues and Primary Intestinal Epithelial Cells of Patients with Active and Inactive Ulcerative Colitis”, project leader: J. Skiecevičienė, funding source: European Crohn’s and Colitis Organisation (ECCO), duration: 2016-2017.
  7. "Volatile biomarkers for early detection and characterisation of gastric and colorectal neoplasms (VOLGACORE)" (grant no. EURONANOMED2-01/2014), project leader: prof. L. Kupčinskas, funding source: EURONANOMED2, duration: 2014-2017.
  8. "Functional role of miR20b, miR451, miR29c, miR125b in pathogenesis of gastric and colorectal cancer" (grant no. MIP-007/2014), project leader: prof. G. Kiudelis, funding source: Research Council of Lithuania, duration: 2014-2016.
  9. "MicroRNA profiling and functional analysis in gastrointestinal stromal tumors" (grant no. MIP-006/2014), project leader: J. Skiecevičienė and L. Kučinskas, funding source: Research Council of Lithuania, duration: 2014 – 2016.
  10. "Development and validation of gastric cancer associated autoantibody test for early gastric cancer detection" (Baltic States-Taiwan project, grant no. TAP LLT 04/2014), project leader: prof. L.V. Jonaitis, funding source: Research Council of Lithuania, duration: 2014-2016.
  11. "Micro-RNA as biomarkers for early diagnosis of premalignant and malignant diseases of gastrointestinal tract" (grant no. VP1-3.1-ŠMM-07-156), project leader: prof. L. Kupčinskas, funding source: EU structural fund, duration: 2011-2015.
  12. "Role of gut microbiota in pathogenesis of pediatric IBD" (grant no. MIP-11217), project leader: prof. G. Kiudelis, funding source: Research Council of Lithuania, duration: 2011-2013.
  13. "Analysis of H.pylori virulence and host response factors in the development of atrophic gastritis in Baltic States and Taiwan" (Baltic states-Taiwan project) project leader: prof. L. Kupčinskas, funding source: Ministry of Education and Science, duration: 2007-2010.
  14. "Prevalence of HFE-hemochromatosis mutations c.845G>A (p.C282Y), c.187C>G (p.H63D) and c.193A>T (p.S65C) in the Lithuanian population" (grant no. T-25/09), project leader: prof. J. Kondrackienė, funding source: Lithuanian State Science and Studies Foundation, duration 2009.
  15. "Molecular mechanism of bacteria recognition in colonic epithelial cells and its association with inflammatory bowel disease etiopathogenesis" (grant no.T-39/08), project leader: prof. G. Kiudelis, funding source: Lithuanian State Science and Studies Foundation, duration: 2008.
  16. "Serological detection of atrophic gastritis and its evolution following H.pylori eradication in areas with high prevalence of H.pylori infection" (Baltic states-Taiwan project), project leader: prof. L. Kupčinskas, funding source: Ministry of Education and Science, duration: 2005-2007.

 

Participation in consortia:

-          International IBD Genetics Consortium, 2011-up to now.

-          European ECCO-EpiCom IBD epidemiology East-West gradient project, 2010-2015.

-          PANcreatic Disease ReseArch (PANDoRA) consortium, 2012-2016- up to now.

-          Gastric Cancer Research (staR) consortium, 2016- up to now.

-          H. pylori world genome project, 2016- up to now.