Laboratory of Clinical and Molecular Gastroenterology
Head of the Laboratory
dr. Jurgita Skiecevičienė
Tel.: (+370 37) 326092
It is the vision of the laboratory to create a systemic understanding of complex human gastrointestinal diseases (inflammatory bowel diseases, premalignant and malignant digestive diseases) as well as rare monogenic gastrointestinal (Wilson’s disease, hereditary hemochromatosis) disorders by using genetic, genomic and metagenomic technologies. This includes the validation of the resulting models on the molecular level (including animal models of the disease) and their translation into the human diagnostic or therapeutic experiment. Clinical research includes epidemiological and clinical aspects of digestive diseases.
The laboratory research staff include geneticists, molecular biologists and clinicians-gastroenterologists. The researchers of the laboratory have published more than 140 research articles, including more than 60 papers in ISI Web of Science journals with impact factor (IF), among them Nature (2012, IF-36, 3), Nature Genetics (2009, 2010, 2011, IF-36), Gastroenterology (2005, 2011, 2013, IF-12), Gut (2006, 2013, 2013, IF-10), Inflammatory bowel diseases (2013, IF- 5.5), Physiological Genomics (2009) and others. The papers were more than 1600 times cited in ISI Web of Science journals (the citation h-index of the research articles by laboratory scientists is 17).