Laboratory of Clinical and Molecular Gastroenterology
Head of the Laboratory
dr. Jurgita Skiecevičienė
Phone. (+370 37) 327236
It is the vision of the laboratory to create a systemic understanding of complex human gastrointestinal diseases (inflammatory bowel diseases, premalignant and malignant diseases of gastrointestinal tract) as well as rare monogenic gastrointestinal (Wilson’s disease, hereditary hemochromatosis) disorders by using genetic, epigenetic, and metagenomic technologies. This includes the validation of the resulting models on the molecular level (including animal models of the disease) and their translation into the human diagnostic or therapeutic experiments. Clinical research includes epidemiological and clinical aspects of digestive diseases.
The laboratory research staff include geneticists, molecular biologists, bioinformaticians and gastroenterologists. The researchers of the laboratory have published more than 140 research articles, including more than 60 papers in Clarivate Analytics Web of Science journals with impact factor (IF), among them Lancet (2016, IF-47.8), Nature (2012, IF-40.1), Nature Genetics (2016-2014, 2011-2009, IF-31.6), Gastroenterology (2013, 2011, 2005, IF-18.3), Gut (2018, 2013, 2006, IF-16.6), Nature Structural and Molecular Biology (2016, IF-13.3), Nucleic Acid Reserach (2017, IF-10.12), Inflammatory bowel diseases (2013, IF- 4.5), and others. The papers were more than 1600 times cited in Clarivate Analytics Web of Science journals (total h-index - 17).