Laboratory of Clinical Physiology and Rehabilitation
On the ground of Laboratory of Cardiology (1978–1991, the chief J. Juskenas; 1992–2001, the chief dr. J. Brozaitiene) and Department (2002–2011) of Cardiovascular Rehabilitation and Prevention (chief J. Brozaitiene) and Clinical Physiology (chief prof. G. Varoneckas) in 2012 Laboratory of Clinical Physiology and Rehabilitation (the chief J. Brozaitiene) was founded.
The main research area: Cardiovascular psychophysiology, cardiac rehabilitation, exercise capacity, heart rate variability, oxygen uptake, sleep, metabolic syndrome.
Researches were performed in the following study programs: 1977–1981 – automatic heart rate variability analysis during functional tests; 1981–1985 – evaluation functional status in CAD patients, dependence on severity of disease, during rehabilitation; 1986–1990 – evaluation functional status in CAD patients during rehabilitation on the basis of heart rate variability during complex functional tests (orthostasis, ergometric and spiroergometric tests, sleep, exercise training procedure); 1991–1995 – individualisation of cardiovascular rehabilitation program in CAD with cerebrovascular disturbances; 1996–2001 – heart rate variability as fast cardiovascular reserve reflection: dependence on leading diseases, basic autonomic disturbances and psychoemotional status; 2002–2006 – evaluation efficacy of rehabilitation in patients after acute myocardial infarction, cardiac revascularization operation, follow-up study and outcomes; 2007–2011 – impact of psychosomatic, neuroendocrine and sleep disturbances on CAD course, rehabilitation and outcomes; 2012–2016 – impact of behavioural and biomolecular factors for cardiovascular disease course, rehabilitation and outcomes and impact meteorological, heliophysical and health resort factors on human health.
Prepared autonomic heart rate variability analysis system allowed to assess standard HRV patterns and Poincare plots, constructed from RR interval sequence, collected during functional tests, considered as useful for their practical purpose (prof. D. Zemaityte). Cardiovascular rehabilitation/secondary prevention program with computerized quantitative evaluation of the integrate parameters of functional status and efficacy of rehabilitation may be useful for country rehabilitation system monitoring. Made-up exercise program with training efficacy evaluation for patients after acute coronary syndromes and cardiac surgery operations is used in rehabilitation institutions. Comprehensive cardiovascular rehabilitation and training program for patients after acute coronary syndrome and cardiac surgery was published in university textbook “Cardiovascular rehabilitation” (Kaunas, 2001) and introduced in Cardiovascular Clinic of institute.
Laboratory colleagues prepared 3 habilitation and 10 doctoral dissertations.
Laboratory is responsible for development rehabilitation optimization methods for patients with CVD as well as for conducting research, concerning informative cardiovascular functional condition indicators in order to prognose the course and outcome of the disease. The research explores the associations of the severity of cardiological condition, biomarkers and genetic indicators, their impact to the patient-oriented outcomes, the course and outcome of an illness among CAD patients who experienced acute coronary syndromes. Currently, new methods of cardiovascular rehabilitation are being developed, which will be based on informative indicators of functional state, cardiovascular system reactions during physical and/or psychoemotional stress tests, and during night time sleep as well as application of feedback
In the laboratory, there are 2 habilitated doctors, 4 doctors of science and 3 PhD students.
Laboratory of Psychosomatic Research
Laboratory of Psychosomatic Research the chief dr. N. Mickuviene. On the 1st of May, 2012 Laboratory of Psychosomatic Research (the chief dr. R. Bunevicius) was founded on the ground of Department of Psychosomatic Investigations (the chief dr. R. Bunevicius) and Department of Informative Technologies and Public Health (the chief dr A. Podlipskyte).
Our laboratory of scientific research is oriented toward developing new psychosocial rehabilitation methods, investigation in biological, psychosocial and related to stress risk factors, as well as physiological, endocrine and other markers of biomolecular values, which are associated with quality of life and survival in patients with cardiovascular diseases (CVD).
The goal of our genetic research is to gain a deeper understanding of psychoemotional disorders at the level of molecular mechanisms. We also aim at prognosing the influence of genes polimorphism related to effect of stress for cardiovascular diseases and mental disorders, and for the results of the treatment. In addition to this, the laboratory also investigates how physical and emotional stress affects cardiovascular and cortisol reactions.
Futhermore, the research is performed concerning utilization of Lithuanian coastal meteorological and helium-geophysical factors for recreation and personal health care. Our studies investigate how climate and meteo-factors affect people‘s physical and mental health. From medical perspective, we also examine the questions concerning unresolved objective medical-meterological clasifications of weather and how it predicts people‘s health. The laboratory assess the impact of Lithuanian seaside resort factors (UV radiation, iodine, anions, cations concentrations, dynamics and determination of its affected area etc.) to people‘s health and their recreation.
In the laboratory, there are 13 scientists, 7 of which are doctors of science and 4 PhD students.